RESET Botanical Ingredients
RANU RESET uses more than 40 carefully selected botanical and nutritional ingredients, organized across three sequential phases. Each ingredient is present because it contributes something the others don't — and because its presence enhances the overall effect.
Dr. Omar M. Amin evaluated over 40 botanical candidates across three years of systematic research (2007–2010), selecting only those with robust scientific evidence. The result is a formula whose complexity is intentional.
Phase Breakdown
Phase 1 — Remove
Ingredients
- Allium sativum Garlic 300 mg
- Punica granatum Pomegranate Peel Extract 250 mg
- Origanum vulgare Oil of Oregano 150 mg
- Juglans nigra Black Walnut Hull 200 mg
- Syzygium aromaticum Clove 100 mg
- Artemisia absinthium Wormwood 120 mg
- Berberis vulgaris Berberine 400 mg
- Citrus paradisi Grapefruit Seed Extract 150 mg
Dosage Instructions
Take 2 capsules in the morning with water, on an empty stomach, at least 30 minutes before breakfast.
Mechanism of Action
Phase 1 — Remove activates the body's natural defenses to identify and eliminate harmful microorganisms, toxins, and parasites that disrupt intestinal balance. Berberine inhibits bacterial and fungal adhesion to the intestinal mucosa, interrupting biofilm formation that shields pathogens. Oil of oregano, rich in carvacrol and thymol, disrupts the cell membranes of bacteria and fungi without harming beneficial flora. Pomegranate peel extract provides punicalagins with potent antioxidant and antimicrobial activity. Garlic, through its active compound allicin, blocks enzymes essential for the survival of opportunistic bacteria and fungi. Black walnut hull and wormwood have been used traditionally to expel intestinal parasites. Grapefruit seed extract complements this action with polyphenols that reinforce the local immune response. This synergistic combination prepares the ground for the restorative and renewal phases.
Warnings
Not recommended during pregnancy or breastfeeding. Consult your physician if taking anticoagulants or diabetes medications. Berberine content may interact with certain drugs. Discontinue use if adverse reactions occur.
Phase 2 — Restore
Ingredients
- Silybum marianum Milk Thistle 300 mg (70% silymarin)
- Taraxacum officinale Dandelion Root 250 mg
- Arthrospira platensis Spirulina 500 mg
- Glycyrrhiza glabra Licorice Root (DGL) 200 mg
- Aloe barbadensis Aloe Vera 150 mg (200:1 concentrate)
- Ulmus rubra Slippery Elm Bark 200 mg
- Curcuma longa Turmeric 250 mg (95% curcuminoids)
- Zingiber officinale Ginger Root 150 mg
Dosage Instructions
Take 2 capsules at midday with food to maximize nutrient absorption and enhance the reparative action during peak digestive activity.
Mechanism of Action
Phase 2 — Restore focuses on repairing the damaged intestinal mucosa and re-establishing optimal digestive function. Silymarin from milk thistle exerts hepatoprotective effects, supporting liver cell regeneration and bile synthesis needed for fat digestion. DGL licorice stimulates mucin production, the protective lining of intestinal walls, reducing increased intestinal permeability. Aloe vera contributes mucopolysaccharides that promote intestinal epithelial healing and exert anti-inflammatory action. Slippery elm bark creates a protective layer over irritated mucous membranes. Turmeric, through its curcuminoids, regulates intestinal inflammatory pathways (NF-κB) and promotes epithelial cell proliferation. Spirulina provides complete proteins, B vitamins, and antioxidant phycocyanin to nourish tissues under repair. Ginger optimizes gastrointestinal motility and reduces local inflammation, supporting the transition into the renewal phase.
Phase 3 — Renew
Ingredients
- Withania somnifera Ashwagandha 300 mg (5% withanolides)
- Eleutherococcus senticosus Siberian Ginseng 200 mg
- Chlorella pyrenoidosa Chlorella 500 mg
- Vaccinium myrtillus Bilberry 150 mg (25% anthocyanins)
- Sambucus nigra Black Elderberry 200 mg
- Camellia sinensis Green Tea Extract (EGCG) 200 mg (50% EGCG)
- Andrographis paniculata Andrographis 150 mg
- Astragalus membranaceus Astragalus Root 250 mg
Dosage Instructions
Take 2 capsules at night before bed. The nocturnal phase optimizes cell repair and detoxification processes that occur naturally during sleep.
Mechanism of Action
Phase 3 — Renew expels the byproducts of eliminated toxins and pathogens, restores digestive balance, and renews intestinal tissue vitality. Chlorella acts as a natural chelating agent, binding to heavy metals and toxic residues to facilitate their safe elimination. Withanolides in ashwagandha modulate the hypothalamic-pituitary-adrenal axis, reducing chronic cortisol that degrades the intestinal barrier. Astragalus and andrographis stimulate immune cell production, strengthening long-term intestinal defense. Bilberry anthocyanins inhibit lipid oxidation in the mucosa and promote beneficial microbiome diversity. Black elderberry extract provides flavonoids that optimize intercellular communication in the renewed intestinal tissue. Green tea EGCG activates autophagy pathways that clear damaged cells and cellular debris. Siberian ginseng as an adaptogen completes the process, restoring energy and systemic balance so the gut can maintain its renewed vitality.
The Power of Botanical Synergy
TL;DR: RESET uses 40+ botanical ingredients because combinations produce effects no single compound can — the 3-year development process was specifically designed to identify the optimal ratios, not just the best individual ingredients.
RESET uses more than 40 botanical and nutritional ingredients rather than a single "active compound" for one reason: synergy. Carefully selected combinations of plant-derived compounds can achieve outcomes no single ingredient produces on its own. Researchers have confirmed that whole-plant compounds interact in complex ways that amplify, modulate, and diversify their effects — sometimes called the entourage effect in botanical literature.
The three-year development process was explicitly designed to identify optimal ratios, not just optimal ingredients. Every ingredient in RESET is present at the concentration the research process determined to be most effective in combination with the others.
Phase 1 — Remove
MorningTake 2 capsules in the morning with water, on an empty stomach, at least 30 minutes before breakfast.
Mechanism of Action
Phase 1 — Remove activates the body's natural defenses to identify and eliminate harmful microorganisms, toxins, and parasites that disrupt intestinal balance. Berberine inhibits bacterial and fungal adhesion to the intestinal mucosa, interrupting biofilm formation that shields pathogens. Oil of oregano, rich in carvacrol and thymol, disrupts the cell membranes of bacteria and fungi without harming beneficial flora. Pomegranate peel extract provides punicalagins with potent antioxidant and antimicrobial activity. Garlic, through its active compound allicin, blocks enzymes essential for the survival of opportunistic bacteria and fungi. Black walnut hull and wormwood have been used traditionally to expel intestinal parasites. Grapefruit seed extract complements this action with polyphenols that reinforce the local immune response. This synergistic combination prepares the ground for the restorative and renewal phases.
Ingredients in Phase 1 — Remove
- Garlic Allium sativum 300 mg
- Pomegranate Peel Extract Punica granatum 250 mg
- Oil of Oregano Origanum vulgare 150 mg
- Black Walnut Hull Juglans nigra 200 mg
- Clove Syzygium aromaticum 100 mg
- Wormwood Artemisia absinthium 120 mg
- Berberine Berberis vulgaris 400 mg
- Grapefruit Seed Extract Citrus paradisi 150 mg
Important: Not recommended during pregnancy or breastfeeding. Consult your physician if taking anticoagulants or diabetes medications. Berberine content may interact with certain drugs. Discontinue use if adverse reactions occur.
Phase 2 — Restore
MiddayTake 2 capsules at midday with food to maximize nutrient absorption and enhance the reparative action during peak digestive activity.
Mechanism of Action
Phase 2 — Restore focuses on repairing the damaged intestinal mucosa and re-establishing optimal digestive function. Silymarin from milk thistle exerts hepatoprotective effects, supporting liver cell regeneration and bile synthesis needed for fat digestion. DGL licorice stimulates mucin production, the protective lining of intestinal walls, reducing increased intestinal permeability. Aloe vera contributes mucopolysaccharides that promote intestinal epithelial healing and exert anti-inflammatory action. Slippery elm bark creates a protective layer over irritated mucous membranes. Turmeric, through its curcuminoids, regulates intestinal inflammatory pathways (NF-κB) and promotes epithelial cell proliferation. Spirulina provides complete proteins, B vitamins, and antioxidant phycocyanin to nourish tissues under repair. Ginger optimizes gastrointestinal motility and reduces local inflammation, supporting the transition into the renewal phase.
Ingredients in Phase 2 — Restore
- Milk Thistle Silybum marianum 300 mg (70% silymarin)
- Dandelion Root Taraxacum officinale 250 mg
- Spirulina Arthrospira platensis 500 mg
- Licorice Root (DGL) Glycyrrhiza glabra 200 mg
- Aloe Vera Aloe barbadensis 150 mg (200:1 concentrate)
- Slippery Elm Bark Ulmus rubra 200 mg
- Turmeric Curcuma longa 250 mg (95% curcuminoids)
- Ginger Root Zingiber officinale 150 mg
Phase 3 — Renew
EveningTake 2 capsules at night before bed. The nocturnal phase optimizes cell repair and detoxification processes that occur naturally during sleep.
Mechanism of Action
Phase 3 — Renew expels the byproducts of eliminated toxins and pathogens, restores digestive balance, and renews intestinal tissue vitality. Chlorella acts as a natural chelating agent, binding to heavy metals and toxic residues to facilitate their safe elimination. Withanolides in ashwagandha modulate the hypothalamic-pituitary-adrenal axis, reducing chronic cortisol that degrades the intestinal barrier. Astragalus and andrographis stimulate immune cell production, strengthening long-term intestinal defense. Bilberry anthocyanins inhibit lipid oxidation in the mucosa and promote beneficial microbiome diversity. Black elderberry extract provides flavonoids that optimize intercellular communication in the renewed intestinal tissue. Green tea EGCG activates autophagy pathways that clear damaged cells and cellular debris. Siberian ginseng as an adaptogen completes the process, restoring energy and systemic balance so the gut can maintain its renewed vitality.
Ingredients in Phase 3 — Renew
- Ashwagandha Withania somnifera 300 mg (5% withanolides)
- Siberian Ginseng Eleutherococcus senticosus 200 mg
- Chlorella Chlorella pyrenoidosa 500 mg
- Bilberry Vaccinium myrtillus 150 mg (25% anthocyanins)
- Black Elderberry Sambucus nigra 200 mg
- Green Tea Extract (EGCG) Camellia sinensis 200 mg (50% EGCG)
- Andrographis Andrographis paniculata 150 mg
- Astragalus Root Astragalus membranaceus 250 mg
Sourcing & Quality Standards
TL;DR: RESET ingredients are sourced from suppliers meeting rigorous botanical identity, purity, and potency standards — with key ingredients using standardized extracts to ensure consistent active compound content.
Botanical integrity depends on the quality of raw ingredients. RESET ingredients are sourced from suppliers meeting rigorous standards for botanical identity, purity, and potency. Each ingredient is quality-tested to verify it meets the specification required to deliver the intended botanical activity.
Botanicals can vary significantly in active compound content depending on growing conditions, harvesting time, processing, and storage. Standardized extracts — where the active compound is measured and guaranteed — provide more consistency than whole-herb preparations. Key RESET ingredients use standardized extract forms where scientifically relevant.
The information on this page is educational and describes traditional uses and research contexts for botanical ingredients. These statements have not been evaluated by regulatory authorities and are not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare professional before starting any new supplement regimen.